Benefits of township living Shortly after the split decision was announced, Thurman readily asked Pacquiao for a rematch.“Much respect to the senator,” Thurman said. “I would love a rematch.”FEATURED STORIESSPORTSGolden State Warriors sign Lee to multiyear contract, bring back ChrissSPORTSCoronation night?SPORTSThirdy Ravena gets offers from Asia, Australian ball clubsIf only for coming out there to fight Pacquiao toe-to-toe, the 30-year-old American—beaten for the first time, and bloodily at that—clearly deserves one.“I think they need to do a rematch,” said Ellerbe, who added that he “thought it was close fight, but I thought it was [a] unanimous” win for Pacquiao. LOOK: LJ Reyes, Paolo Contis celebrate 1st birthday of baby Summer Will you be the first P16 Billion Powerball jackpot winner from the Philippines? Sons Of Apollo releases new studio album ‘MMXX’ LATEST STORIES ‘Marawi hero’ is new commander of Army’s 1st Infantry Division But Ellerbe didn’t bother to answer a Mayweather-Pacquiao rematch of their 2015 megafight, which was the biggest ever in boxing in terms of revenues.Young turks Errol Spence Jr., and Shawn Porter were at ringside. They will clash on Sept. 28 with the winner getting the inside track in the Pacquiao sweepstakes.Though the fight tarnished Thurman’s once immaculate record, he proved his worth against one of boxing’s greatest.“This guy,” Pacquiao said of Thurman. “He can fight, he has a lot ahead of him. His journey does not end here. Don’t be discouraged [with] this part of boxing [losing]. This guy is a warrior.”Thurman matched his brashness in words by coming back despite the punishments.ADVERTISEMENT Manny Pacquiao (L) and Keith Thurman battle in the 10th round of their WBA welterweight title fight at MGM Grand Garden Arena on July 20, 2019 in Las Vegas, Nevada. Pacquiao won in a split decision. Ethan Miller/Getty Images/AFPLAS VEGAS—If Floyd Mayweather is no longer an option, Manny Pacquiao still has plenty of choices for his next fight.But if you ask Mayweather Promotions chief Leonard Ellerbe, a rematch with Keith Thurman is the most logical.ADVERTISEMENT Trending Articles PLAY LIST 00:50Trending Articles00:44Manny Pacquiao on Floyd Mayweather: Let him enjoy retirement01:49Pacquiao to Mayweather: Want fans to stop asking for rematch? Then fight me again02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award03:05Malakanyang bilib sa Phivolcs | Chona Yu01:26Homes destroyed after Taal Volcano eruption02:48ABS-CBN franchise has ‘natural deadline,’ no need for quo warranto — Gatchalian MOST READ View comments He survived a stunning knockdown in the first, a busted nose in the fifth, and a sledge-hammer punch to the solar plexus in the 10th.“Tonight was a great night of boxing,” Thurman said. “You know, the opening round didn’t start the way that I wanted to. Manny Pacquiao had a lot of momentum from the knockdown.”“I ended up paying attention to the rounds, by the time we got to seven, I said ‘Hey we’re [in the] seventh already,’” he added. His trainer Dan Birmingham then instructed him to try to win every round thereafter.Thurman’s record fell to 29-1 (22 knockouts), while Pacquiao went up 62-7-2 (39 KOs).At any rate, Pacquiao said he won’t fight anymore this year.“I have to go back to my work in the Senate,” said Pacquiao, who , contrary to original plans, won’t make it to President Duterte’s State of the Nation Address on Monday.Sports Related Videospowered by AdSparcRead Next Top seeds in trouble Steaming fissures on Taal Volcano Island spotted Duterte lambasts Catholic Church anew in curse-laden speech before Filipino Baptists MRT-3 files raps vs engineer who brought ammunition to station Don’t miss out on the latest news and information.
Has the new manager bounce worn off for Jose Mourinho at Manchester United already? The former United, Portsmouth & Southampton midfielder Alan McLoughlin asks what United fans were expecting!Also, can West Ham’s leaky defence hold firm against the Saints at the London Stadium on Sunday?Chelsea bounced back from their first loss of the season with an EFL Cup win at Leicester. Now, the former Blues defender Michael Duberry is calling for better defending from Antonio Conte’s side and a recall to the starting line-up for Cesc Fabregas.Tom Rennie hosts.
Jefferson Montero 1 Swansea winger Jefferson Montero has joined Spanish side Getafe on a season-long loan, subject to international clearance.The Swans announced on their official website that the Ecuador international had moved to LaLiga in search of “regular football”, having been plagued by injury issues last season.The 28-year-old, who moved to the Liberty Stadium in 2014, is under contract in south Wales until 2020.
Ex-Everton defender Alan Stubbs believes the Toffees have lost their principles due to the money the club have spent.The Goodison Park side find themselves in the relegation zone after a dreadful start to the season, despite heavy investment into new players over the summer.Speaking to talkSPORT, the 46-year-old believes the club have lost sight of what they are.He said: “I think this money has clouded the judgement of what we stand for as a football club.“We’ve got principles and morals as a club, as David Moyes would say – we’re a people’s club, we’re a hard working club, we know what we are.“I think the money has made us get ahead of ourselves and suddenly think we’re going to challenge for the top four, which was never going to be.”The Blues are yet to appoint a new manager since the sacking of Ronald Koeman and Stubbs urges the club to be realistic.He added: “As soon as Koeman got the sack, fans were saying we want Ancelotti and I’m thinking, come on, we have to be realistic here.”
boost LATEST FOOTBALL NEWS Liverpool update ‘Champions Wall’ after ending 2019 as European and world champions Arsenal transfer news LIVE: Ndidi bid, targets named, Ozil is ‘skiving little git’ The 27-year-old signed for a world record fee in 2017 but he has not settled in the French capital.Cardoner explained the current situation with the Brazil international.“What I believe is that Neymar wants to come back,” Cardoner said. “But to say we are working on recruiting him, that is something cannot agree with. The biggest market value losers in 2019, including Bale and ex-Liverpool star JIBE Man United transfer news live: Haaland ‘wants a change’, two players off in January Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 1:23Loaded: 11.91%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -1:23 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreen Tottenham issue immediate ban to supporter who threw cup at Kepa latest Lampard appears to aim dig at Mourinho for handling of Salah and De Bruyne at Chelsea punished Ally McCoist is not a Neymar fan and thinks he is ‘classless’ “It doesn’t surprise me that Neymar wants to come back to Barcelona.“What seems true is that he wants to come to Barca.“We don’t know if it will come to a good conclusion. It’s not correct that we have signed Neymar.“It’s the action-reaction that happens with some players, it’s not the first time, there are cases like Cesc and Pique.“He’s a great player, that part is indisputable, the circumstances in which he left were special. 1 Neymar wants a move away from Paris Saint-Germain deals “There are things about his departure I don’t understand, we have to look over a lot of things that happened and change some scenarios.”Reports had suggested that Neymar may go on strike in order too force a move back to the LaLiga champions.There had also been suggestions that a contract had already been agreed, which would force him to take a large pay cut. Solskjaer gives Pogba fitness update and calls him world’s best all-round midfielder Barcelona vice-president Jordi Cardoner has revealed he ‘doesn’t know’ if a deal to bring Neymar back to the club will happen.Talks are reportedly in the early stages over a potential transfer for the Paris Saint-Germain star just two years after he left the Nou Camp. LATEST REVEALED TROPHY Liverpool news live: Klopp reveals when Minamino will play and issues injury update Getty
Glen Davis Wells, age 87, of Borden, Indiana, passed away Saturday January 5, 2019 at his residence. Born on October 25, 1931 in Borden, he was the son of the late Elmo Harbin Wells and Florence Gertrude Harned Wells.Glen delivered the Grit Paper to all everyone around Borden. He enjoyed his garden and loved the outdoors.He is survived by his sister, Roberta Karnes and her husband Kermit, of Borden. He is preceded in death by his parents; 2 brothers, Charles Warren Wells and Bobby Wells.The funeral service will be at 11:00 AM Tuesday at the Hughes-Taylor Funeral Home in Borden. Viewing will be Monday from 4-8 PM and Tuesday from 9:00 AM until time of service at the funeral home. Burial will be at Mt. Washington Cemetery.
Share This!It’s been officially announced as being pushed back. According to the OC Register, World of Color will not be returning to Disney California Adventure this year. Instead, it will now reopen sometime in 2019, but it doesn’t look like the show will be returning any time soon, as Disney says it may still be months before it’s back again.The nighttime spectacular has been closed since April due to unexplained circumstances that occurred during routine maintenance. No one is saying what happened, but the problem was large enough to shut the show down unexpectedly. Rumors indicate that during the regularly scheduled maintenance that occurred in April, components that run the show that were supposed to be submerged in the lagoon were damaged, therefore requiring extensive repairs.The World of Color show, which has been popular since it debuted in 2010, features a beautiful water show, including fountains, light, and music.
During the 2013 Intel IT Experts Tour, an audience of IT professionals showed great concern and interest in the challenges of protecting their computing environments from cyber security threats. As part of Intel’s IT outreach program, I discussed the state of security, IT challenges, and audience’s concerns with protecting their electronic ecosystem, users, and information. Key Points:IT and security professionals must communicateComputing trends add to rising complexity for securityMalware growth represents investments by attackersPeople, not just technology, are part of the security problemAttacks are moving down the stack to hardwareLayered and Defense-in-Depth strategies are crucial for comprehensivenessHardware enhanced security enriches protectionIntel and McAfee are committed to be trusted security advocates and partners Intel security professionals regularly reach out in open and candid discussions to help the IT community. Intel is committed to help keep computing safe and be a trusted advocate of security.Intel hosts the IT Experts Tour where business professionals can come together and discuss pressing IT and security topics. Find out more at the IT Center and IT Experts webinar and live events page.Where to find me:In Person: Delivering a keynote presentation at Cyberstrat 2014 in Helsinki on January 22.On Twitter: @Matt_RosenquistMy Blog: Information Security StrategyIT Peer Network: My previous postsMy work: Linkedin
Fueled by hundreds of millions of grant dollars, biomedical researchers have begun sequencing the genomes of thousands of tumor samples in the past few years, linking up scores of labs and sequencing centers in a massive effort to identify the genes behind major cancers. But a leading cancer geneticist this week questioned whether this strategy still makes sense. The skeptic is Bert Vogelstein, who spoke at a Monday plenary session on cancer genomes at the annual meeting of the American Association for Cancer Research in Washington, D.C. Vogelstein looked across all the studies published since 2007 that have sequenced the 21,000 or so protein-coding genes involved in cancer, known as the cancer “exome.” The analysis covered 78 tumor samples and eight cancer types (the majority of the studies were done by Vogelstein’s group). Vogelstein also threw in data for 22 medulloblastomas (a type of brain tumor) that his team has not yet published. Even at this early stage of the planned survey–with data on just 100 tumor samples—”we can already answer many of the fundamental questions about the cancer genome,” Vogelstein said. For example, tumors typically have from 30 to 80 single-base mutations, except for types that take less time to develop such as leukemia (about 10 mutations). Melanoma and lung cancer round out the high end (100 to 200 mutations) because they are caused by environmental carcinogens that cause lots of mutations. (Deletions and amplifications add a few more genetic glitches.) To Vogelstein this looked like the outline of a basic pattern that won’t change much. But he gathered some more details. Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) Vogelstein searched databases for all mutations in genes found in solid cancers in the past 2 decades; for 353 cancer subtypes, he came up with 130,072 mutations in 3142 genes. But not all contribute to cancer. The challenge is to figure out which mutations are “drivers” and which are “passengers.” To pick out the drivers, Vogelstein assumed that mutations in suppressor genes had to truncate the gene’s protein; for oncogenes he included only mutations seen in at least two tumors. That distilled the gene count to just 319 potential driver genes, 286 of them tumor suppressors and 33 oncogenes. Nearly all these genes fall into 12 “core” signaling pathways, Vogelstein said. And that picture—about 320 genes in 12 pathways–is unlikely to change much even when thousands more tumor samples are sequenced, he argued. So far, the cancer exome projects have found only two new driver genes ( IDH1/2 in glioma and FOXL1 in granulosa tumors). Vogelstein predicts that most new driver mutations will be rare; and nearly all will be part of same 12 pathways. It may make more sense to target drugs on these pathways than on genes, Vogelstein said. That’s partly because 90% of the 320 driver mutations are tumor suppressors, which aren’t good drug targets. To treat such a mutation you must turn a gene that’s off back on, which is hard to do. Vogelstein summed up by saying that cancer has gone from “a complete black box” to something that “we really kind of understand.” The “sobering” part, he said, is that he doesn’t expect there will be many new genes or genetic breakthroughs. He has pinned his own hopes for preventing cancer deaths on using genetics to diagnose cancers early, when they’re more treatable. Vogelstein isn’t the only one questioning the wisdom of pricey cancer genome projects. (The U.S. National Cancer Institute’s Cancer Genome Atlas (TCGA), the main one, has cost $375 million so far; it is part of an international cancer genome consortium that aims to sequence 25,000 tumor samples for a total of $1 billion.) The Massachusetts Institute of Technology’s Robert Weinberg told ScienceInsider that he considers TCGA “money poured down a hole. Sequencing endless more cancer genomes isn’t going to tell us more than we already know.” But cancer geneticist Todd Golub of the Broad Institute in Cambridge, Massachusetts, who recently debated the cancer genome projects with Weinberg in Nature, disagrees. There’s more to be learned by finding rare mutations, he says. “There will be some pathways we don’t know about that are totally new,” Golub says, and “we won’t get that out of a few genomes.” UPDATE 4/26/2010:NCI’s Anna Barker and Mark Guyer of the National Human Genome Research Institute, who oversee The Cancer Genome Atlas, told ScienceInsider that they’re not persuaded by Vogelstein’s argument that 100 tumor genomes are enough to predict what will be learned from many more cancer genomes. “That’s a nice opinion, and where’s the data to demonstrate it?” says Guyer. Adds Barker: “I am stunned that he [Vogelstein] made some of these comments.” She says that having “a robust set of samples and a robust set of data” is already providing insights that can’t be gleaned from smaller studies, such as delineating clinical subtypes of gliomas based on epigenetics. “The thing that really differentiates this project from anything done in the history of medicine to date is that it’s really moving us towards quantitative cancer biology,” Barker says.
Sydney hashtag debacle spells bad news for the ‘people’s channel’. Related Items